How many grams of glycogen can the liver store at maximum?

The liver can store approximately 100 grams of glycogen at maximum capacity. This storage capacity serves a crucial physiological role, as the glycogen stored in the liver is primarily used to maintain blood glucose levels, especially during fasting or periods of low carbohydrate intake. This glycogen can be mobilized into glucose through a process called glycogenolysis, ensuring that the body has a readily available energy source when needed.

In the context of overall energy metabolism, the liver's glycogen stores are critical for supporting brain function and muscle activity during exercise. While skeletal muscles also store glycogen, their storage capacity is distinct and generally much higher, but that glycogen is primarily used for muscle contraction and energy during physical activity, not for maintaining blood sugar levels. This differentiation highlights the liver's unique role in overall metabolism and energy homeostasis.